AutoSNP

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Redundancy based detection of sequence polymorphisms in expressed sequence tag data using autoSNP

  • 주소:  <html>dave.edwards@nre.vic.gov.au</html> (저자)
  • Web server/Application: Application
  • 국가명: 영국, 호주
  • 만든 곳: Institute of Arable Crop Research, Long Ashton
    Agriculture Victoria Plant Biotechnology Centre, La Trobe University
    School of Biological Sciences, University of Bristol BS8 1UG
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  • 내용: AutoSNP는 하나의 뉴클레오타이드 다형성체(SNP)의 분석과 발현된 서열태드(EST)데이터의 삽입/결실 다형성을 분석하기 위한 프로그램이다. 이 프로그램은, EST 순서를 클러스터로 나누어 정렬시키기 위해서 d2cluster와 cap3를 사용해, 후보 SNP 및 순서·에러를 구별하기 위해서 잉여를 사용한다.
    (AutoSNP is a program to detect single nucleotide polymorphisms (SNPs) and insertion/deletion polymorphisms (indels) in expressed sequence tag (EST) data. The program uses d2cluster and cap3 to cluster and align EST sequences, and uses redundancy to differentiate between candidate SNPs and sequence errors. Candidate polymorphisms are identified as occurring in multiple reads within an alignment. For each candidate SNP, two measures of confidence are calculated, the redundancy of the polymorphism at a SNP locus and the co segregation of the candidate SNP with other SNPs in the alignment.)